Big update to database and MOREPEAKS

We have added about 200 more publications to the 2D-LC method database, a collaboration between the University of Amsterdam and Gustavus Adolphus College. The database now covers almost all methods from 1978 until present. Please advise us of any papers we might have missed through the special option in the menu.

We also are pleased to announce that the first prototype of Multivariate Optimization and Refinement Program for Efficient Analysis of Key Separations (MOREPEAKS) is scheduled to be shared on this website towards the end of the year. The initial version will contain data-analysis tools for 1D-LC and 2D-LC, with support for MS data, exclusion chromatography and calibration. The program will also comprise the first public prototypes of the method-optimization tools for multi-dimensional LC.

Update 2D-LC method database

The 2D-LC method database – a collaboration between the University of Amsterdam and Gustavus Adolphus College – has been doubled in size with the addition of all methods from 2011 until 2015. The layout and presentation has furthermore been optimized based on feedback. We continue to update the database backwards in time. We are also further investigating other helpful tools to search and filter the database.

The maintenance and processing of literature into this database is manual, human work which involves a lot of reading and thus may contain errors. You can help out by checking whether your own publications have been processed correctly.

On a side note, there is – of course – also a large amount of useful literature which does not encompass an application. These papers do thus not appear in the database. We are looking into how to efficiently present them on another page.


Thank you for visiting. On this website you will be able to find more information on the work by Bob Pirok and colleagues. The website also aims to provide a useful repository of information concerning the application and implementation of multi-dimensional chromatography, including computer-aided method development and data analysis.

While we continue to add more useful components and expand existing one to complete the initial phase of this website, please note that some elements on this website are still under construction.

We also intend to publish the first public version of our 2DLC method optimization software on this website in the near future, as well as useful publications and guides. One first-version example is the guide on modulation, which we will expand with tips on application. Finally, we will provide reports of conferences.

For the moment, we would like to draw your attention to the searchable 2D-LC method database, containing all applications of 2D-LC since 2016. We are currently in the process of updating it backwards to ultimately include all 2D-LC methods. We also refer you to the 2D-LC Oppurtunities and Challenges table, which we update routinely to reflect the state-of-the-art developments.

Thank you.

Kind regards,
Bob Pirok